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Two patients with proved visceral leishmaniasis were studied with radio-iron 59Fe and radio-chromium 51Cr respectively, in an attempt to elucidate some of the mechanisms producing anaemia in this disease. The red cell life span was shown to be greatly reduced, with sequestration and probable haemolysis occurring in the spleen. The ferrokinetic studies suggested a mild degree of ineffective erythropoiesis. Blood volume determinations were normal.
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Knight et al. (1967) studied this question.
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