Key result
Brugada syndrome triggers VF in relatively healthy individuals with coved-type STE.
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Brugada syndrome (BrS) was introduced in the early 1990s as “primary electrical disease” that caused ventricular fibrillation (VF) in relatively healthy individuals who had coved-type ST-segment elevation in right precordial electrocardiographic (ECG) leads,1 and it was thought to be due to repolarization abnormality from ion channelopathy due to molecular genetic defects.2 Around the same time, the US Centers for Disease Control and Prevention identified an alarming increase in sudden nocturnal unexplained deaths among Laotian and Cambodian refugees in the United States.
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Koonlawee Nademanee (2021) conducted a review in Brugada syndrome. Radiofrequency ablation was evaluated. Brugada syndrome is a primary electrical disease causing ventricular fibrillation in relatively healthy individuals with coved-type ST-segment elevation.
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