Key result
Treatment of adult chicken skeletal myofibrils with a myosin-extracting solution revealed 10 nm intermediate filaments connecting Z-bands along the length of the myofibril.
Population
Adult chicken skeletal myofibrils
Comparison
Treatment with a myosin-extracting solution vs Control (unextracted myofibrils)
Design
Preclinical
Authors
Loading...
Hypothesis-generating for sarcomere stability in striated muscle; leaves open relevance to mammalian cardiac myofibrils.
Identifies intermediate filaments as an integral part of the sarcomere connecting Z-bands in skeletal muscle.
Price et al. (1979) studied this question. Myosin-extracting solution was evaluated on Sarcomere length and filament characteristics. Treatment of adult chicken skeletal myofibrils with a myosin-extracting solution revealed 10 nm intermediate filaments connecting Z-bands along the length of the myofibril.