Key result
Aortic valve-preserving surgery improves survival over replacement for AR despite a long learning curve.
Why the study?
Despite offering survival benefits over valve replacement for aortic regurgitation, aortic valve-preserving surgery has not been widely adopted due to technical complexity, prompting a review of recent technical and theoretical advances.
Does aortic valve-preserving surgery improve survival compared to mechanical or biological aortic valve replacement in patients with aortic regurgitation?
Does aortic valve-preserving surgery improve survival compared to mechanical or biological aortic valve replacement in patients with aortic regurgitation?
Aortic valve-preserving surgery is emerging as a beneficial alternative to valve replacement for aortic regurgitation, supported by recent technical advances and standardization.
May inform AR surgical decisions in experienced centers; extends observational data but leaves open need for RCTs.
The natural history of aortic regurgitation is not as benign as once believed, even in asymptomatic patients with preserved left ventricular function. Aortic valve surgery can prolong survival in these patients. However, both mechanical and biological aortic valve replacement have major disadvantages, especially in young patients. Aortic valve-preserving surgery has attracted a great deal of attention because it has a significant survival benefit over replacement. Nonetheless, aortic valve-preserving surgery has not been widely adopted due to the complexity of the technique and assessment (i.e., long learning curve). With recent technical and theoretical advances, aortic valve-preserving surgery has increasingly been performed with better outcomes, and therefore earlier surgical intervention in cases of aortic regurgitation has been considered. Recent advances in aortic valve-preserving surgery include repair-oriented classification of the etiology of aortic regurgitation, objective assessment of the cusp configuration (i.e., effective height and geometric height), use of aortic annuloplasty, introduction of two reproducible valve-sparing root replacement procedures (i.e., aortic valve reimplantation and aortic root remodeling techniques), standardization of aortic valve-preserving surgery, and assessment of cusp configuration with aortoscopy. A number of prospective multicenter studies are currently underway and will clarify the role of aortic valve-preserving surgery in the treatment of aortic regurgitation in the near future.
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Takashi Kunihara (2020) conducted a review in Aortic regurgitation. Aortic valve-preserving surgery vs. Aortic valve replacement was evaluated. Aortic valve-preserving surgery for aortic regurgitation is increasingly performed due to recent technical advances, offering a survival benefit over replacement despite a long learning curve.
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