Key result
ICAROS registry evaluates echographic plaque characteristics and 1-year embolism and restenosis risk after carotid stenting.
Why the study?
Does echographic plaque echodensity (gray-scale median) predict the risk of periprocedural stroke and restenosis in patients undergoing carotid artery stenting?
Observational
Yes
Does echographic plaque echodensity (gray-scale median) predict the risk of periprocedural stroke and restenosis in patients undergoing carotid artery stenting?
The ICAROS registry aims to establish echographic criteria to improve patient selection and reduce cerebral embolization risk during carotid artery stenting.
May inform plaque-based risk stratification for carotid stenting; leaves open prospective validation of gray-scale median for embolism or restenosis.
ICAROS (Imaging in Carotid Angioplasties and Risk Of Stroke) is a multicenter international registry of carotid artery stenting designed to determine the criteria for identifying patients at higher or lower risk of periprocedural stroke and restenosis at 1 year. The aim of the registry is to improve patient selection and consequently reduce the risk of cerebral embolization during carotid stenting. The registry is open to all interventionists performing carotid stenting, and the participants are free to apply their own endovascular techniques and devices, including cerebral protection mechanisms. All cerebral ischemic events following the procedure will be reported. Follow-up surveillance to 1 year will include periodic duplex scanning and neurological examinations. Echographic plaque images will be standardized for comparison, processed for echodensity, and analyzed by computer at the Registry Center. Correlation will be investigated between the echographic index (gray-scale median) and the risk of embolism and outcome of carotid stenting.
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Biasi et al. (2001) conducted an observational in Carotid artery disease. Carotid artery stenting was evaluated on Periprocedural stroke and restenosis at 1 year. The ICAROS registry was designed to evaluate the correlation between echographic plaque characteristics and the risk of embolism and restenosis at 1 year following carotid artery stenting.
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