Answers are grounded in this paper and cite their sources.
Various hormone-sensitive lipase (HSL) inhibitors, such as oxadiazolones, 2H-isoxazol-5-ones and carbamoyltriazoles, were evaluated for their fatty acid amide hydrolase (FAAH) and monoglyceride lipase (MGL) inhibitory potencies. All compounds inhibited both enzymes with IC50 values varying from the nanomolar to low micromolar range. The compounds may serve as lead structures in the development of novel and potentially selective FAAH and MGL inhibitors.
No takes yet. Share an insight, caveat, or question.
Minkkilä et al. (2009) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: