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November 2, 2015Genes to CellsOpen Access

Relative contribution of four nucleases, CtIP, Dna2, Exo1 and Mre11, to the initial step of DNA double‐strand break repair by homologous recombination in both the chicken DT40 and human TK6 cell lines

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Authors

RARemi AkagawaLife Science InstituteTYTomomi YamasakiKHKouji HirotaTokyo Metropolitan University

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Akagawa et al. (2015) studied this question.

synapsesocial.com/papers/6aa13aae5d3d8bc9fa8429c0https://doi.org/10.1111/gtc.12310
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Two different Swi5-containing protein complexes are involved in mating-type switching and recombination repair in fission yeast2003 · 138 citations
  2. 2MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA2012 · 69 citations