Key result
Blood transfusion is linked to increased RVEF at 72 hours with no change in LVEF.
Why the study?
Does blood transfusion change cardiac ejection fraction up to 72 h in patients with chronic anaemia?
Observational (n=32)
Does blood transfusion change cardiac ejection fraction up to 72 h in patients with chronic anaemia?
Transfusion of small amounts of RBCs in patients with chronic anemia does not significantly alter LVEF up to 72 hours, but may increase RVEF.
Answers are grounded in this paper and cite their sources.
Small-volume transfusion should not yet change practice in chronic anemia; hypothesis-generating for selective RVEF increase at 72 hours.
The objective was to assess the serial change of the cardiac function after blood transfusion in patients with chronic anaemia. According to a previous study, transfusion would adjust the ejection fraction to the advantage of cardiac function in chronic anaemia patients, and thus the serial change of the cardiac function in a certain period should be evaluated after transfusion in patients with chronic anaemia. In a prospective study, ejection fraction (EF) was determined before and < or = 6 h, 24 h and 72 h after transfusion in 32 patients with chronic anaemia, and the results were compared and analysed. In the left ventricle (LV), the four EFs noted before and < or = 6 h, 24 h and 72 h after transfusion did not significantly differ between one another. In the right ventricle (RV), the EF 72 h after transfusion significantly increased in comparison with the pretransfusion value (P = 0.043). Transfusion of small amounts of RBC did not significantly change the LVEF up to 72 h in patients with transfusion-dependent chronic anaemia; whether it might change the RVEF 72 h after transfusion deserves further investigation.
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Chao‐Hung Ho (2001) conducted an observational in Chronic anaemia (n=32). Blood transfusion vs. Pretransfusion baseline was evaluated on Serial change of cardiac ejection fraction (LVEF and RVEF) (p=0.043). Blood transfusion did not significantly change left ventricular ejection fraction up to 72 hours, but right ventricular ejection fraction significantly increased at 72 hours (P=0.043).
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