An objective method for evaluating the suitability of different hollow fibers as separation channels in hollow-fiber flow-FFF is presented. The method is applied to evaluate four different fiber types and to compare several fibers of the same type. It is shown that the maximum plate number achievable with a certain fiber is governed by the homogeneity of the distribution of pores in the fiber wall. The method makes it possible to distinguish and measure the contribution to the peak width that originates from the inhomogeneity in pore distribution.
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Carlshaf et al. (1993) studied this question.
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