Key result
Elevated pre-cardioversion TDI negative systolic wave velocity predicts 100% AF recurrence.
Why the study?
Does Tissue Doppler imaging (TDI) analysis at pre-cardioversion time predict recurrent atrial fibrillation in patients undergoing successful electrical cardioversion?
Cohort (n=94)
Does Tissue Doppler imaging (TDI) analysis at pre-cardioversion time predict recurrent atrial fibrillation in patients undergoing successful electrical cardioversion?
Pre-cardioversion Tissue Doppler Imaging, specifically a negative systolic wave velocity >5.43 cm/sec, strongly predicts atrial fibrillation recurrence at 1 year following successful electrical cardioversion.
May aid post-cardioversion AF recurrence risk stratification; hypothesis-generating and requires prospective validation before practice change.
INTRODUCTION: Tissue Doppler imaging (TDI) has been extensively used in several clinical settings. We aimed to investigate whether TDI can predict recurrent atrial fibrillation (AF). METHODS AND RESULTS: Seventy-four consecutive patients (aged 62.6 +/- 11.7 years) with AF (>48 hours and <6 months of duration) who underwent successful external electrical direct current cardioversion and 20 healthy individuals were enrolled. Conventional echocardiography and TDI were prospectively performed before cardioversion. Based on a cutoff point of 5.43 cm/sec for the negative systolic wave velocity (NSWV), derived by the normal controls (mean + 2 SD), patients were divided into Group I (36 patients) with a NSWV >5.43 cm/sec and Group II (38 patients) with NSWV 48 hours; all patients were in AF at 12 months. In Group II, all patients were in sinus rhythm at 12 months. However, those patients presenting with a NSWV less but near to 5 cm/sec had frequent episodes of asymptomatic paroxysmal AF lasting for <48 hours. CONCLUSION: One year after successful direct current cardioversion, TDI analysis at pre-cardioversion time may be a useful marker to identify a subgroup of patients with increased risk for AF recurrence.
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Paraskevaidis et al. (2006) conducted a cohort in Atrial Fibrillation (n=94). Negative systolic wave velocity (NSWV) >5.43 cm/sec vs. NSWV <5.43 cm/sec was evaluated on Recurrent atrial fibrillation at 12 months. Pre-cardioversion tissue Doppler imaging with a negative systolic wave velocity >5.43 cm/sec predicted a 100% rate of recurrent atrial fibrillation at 12 months, compared to 0% in those below the cutoff.
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