Key result
A PA-TDI interval cutoff of 152 milliseconds predicted early recurrent atrial fibrillation after successful cardioversion with 87% sensitivity and 100% specificity.
Why the study?
Does total atrial conduction time assessed by tissue Doppler imaging predict early recurrence of persistent atrial fibrillation after successful electrical cardioversion?
Cohort (n=54)
Does total atrial conduction time assessed by tissue Doppler imaging predict early recurrence of persistent atrial fibrillation after successful electrical cardioversion?
p-value: p=<0.00001
Total atrial conduction time measured by tissue Doppler imaging (PA-TDI interval >152 ms) is a highly sensitive and specific predictor of early atrial fibrillation recurrence after successful electrical cardioversion.
BACKGROUND: The aim of this study was to investigate whether total atrial conduction time (TACT) assessed via tissue Doppler imaging (PA-TDI interval) can identify patients with early recurrent atrial fibrillation (ERAF) after successful direct-current electrical cardioversion (CV) of persistent atrial fibrillation (persPAF). METHODS AND RESULTS: A total of 54 patients without antiarrhythmic drug medication (mean ± SD: 66 ± 10.4 years; 33% women) with persPAF and successful CV were enrolled between May 2012 and May 2013. TACT was measured 6 hours after successful CV in the left atrium by tissue Doppler imaging (PA-TDI interval). ERAF was determined via Holter-electrocardiogram over a period of 7 days after CV. Receiver opearting characteristic analysis was used to determine an optimal cutoff value of PA-TDI interval for prognosis of ERAF. Based on this result, recurrence-free survival was assessed with Mantel-Haenszel's log-rank test. ERAF occurred in 23 patients (43%). PA-TDI interval was longer in patients with ERAF compared to those who maintained sinus rhythm (mean ± SD: 163.5 ± 11.1 vs 132.3 ± 11.2 milliseconds; P < 0.00001). At the cutoff value of 152 milliseconds, PA-TDI interval sensitivity and specificity related to ERAF were 87% and 100%, respectively. CONCLUSION: Measuring PA-TDI interval may help to predict ERAF after successful CV in patients with persAF.
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Müller et al. (2013) conducted a cohort in Persistent atrial fibrillation (n=54). PA-TDI interval (total atrial conduction time) was evaluated on Early recurrent atrial fibrillation (ERAF) (p=<0.00001). A PA-TDI interval cutoff of 152 milliseconds predicted early recurrent atrial fibrillation after successful cardioversion with 87% sensitivity and 100% specificity.
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