Key result
Discontinuing the offending drug yields clinical improvement in serotonin syndrome typically within 24 hours.
Serotonin syndrome is a clinical diagnosis requiring prompt recognition and immediate discontinuation of the offending agent, with Hunter's criteria offering improved diagnostic sensitivity and specificity.
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Supports immediate serotonergic drug cessation in suspected cases; leaves open need for trials on adjunctive therapies in severe presentations.
Mohd Faisal Uddin (2017) conducted a review in Serotonin Syndrome. Discontinuation of offending drug was evaluated. Discontinuation of the offending drug is the mainstay of treatment for serotonin syndrome, with clinical improvement typically seen in most patients within 24 hours.
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