Key result
Viral challenge causes hydropericardium lesions and liver necrosis in chicks on day six without early symptoms.
Population
175 one-day-old broiler chicks
Comparison
Vaccination with 0.2 ml dose followed by viral… vs Non-vaccinated chicks challenged with the same…
Design
Preclinical
Follow-up
6 days post challenge
Authors
Loading...
Indicates delayed lesion onset in challenged chicks; hypothesis-generating for hydropericardium syndrome in poultry models.
The study describes the in vivo pathogenicity and histopathological liver changes of hydropericardium hepatitis syndrome in broiler chicks following viral challenge.
Shahzad Akbar Khan Mughal (2011) studied Hydropericardium hepatitis syndrome (Angara disease) (n=175). Vaccine vs. Non-vaccinated chicks was evaluated on Clinical manifestation of disease and histopathological lesions. Following viral challenge, chicks showed no clinical manifestation up to 5 days but exhibited hydropericardium lesions and liver necrosis on day 6.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: