Answers are grounded in this paper and cite their sources.
An unprecedented highly enantioselective cascade oxa-Michael-Michael reaction has been developed. The simple and practical process, efficiently catalyzed by chiral diphenylprolinol TMS ether, affords a powerful access to highly functionalized synthetically useful chiral chromans. Moreover, notably a new activation mode involving an aminal is disclosed for the first time.
No takes yet. Share an insight, caveat, or question.
Zu et al. (2009) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: