Key result
Fixed-dose atorvastatin/perindopril cuts LDL ~53% and normalizes blood pressure in a 39-year-old man.
Why the study?
Targeting multiple risk factors can achieve greater cardiovascular risk reduction, particularly in younger patients, using fixed-dose combinations for hypertension and dyslipidemia.
Does a fixed combination of atorvastatin and perindopril improve lipid profile and blood pressure in a young man with hypertension and dyslipidemia?
Case Report (n=1)
Does a fixed combination of atorvastatin and perindopril improve lipid profile and blood pressure in a young man with hypertension and dyslipidemia?
A fixed-dose combination of atorvastatin and perindopril effectively managed both hypertension and dyslipidemia in a young male patient.
Hypothesis-generating for fixed statin-ACEi use in young patients with hypertension and dyslipidemia; prospective trials needed before clinical adoption.
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Ľubica Cibičková (2020) conducted a case report in Hypertension and dyslipidemia (n=1). Fixed combination of atorvastatin and perindopril (Euvascor) vs. Baseline (perindopril 2.5 mg/day alone) was evaluated on Lipid profile and blood pressure control. Treatment with a fixed combination of atorvastatin and perindopril (40/5 mg) in a 39-year-old man improved blood pressure from 140/100 to 120/80 mmHg and reduced LDL cholesterol from 3.87 to 1.80 mmol/l.
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