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A potential warfarin -voriconazole interaction has been identified in one study involving healthy individuals.We report a case where addition of voriconazole possibly increased the international normalized ratio (INR) in a renal transplant patient taking warfarin.The INR elevation was resistant to reversal agents, and the situation may have ultimately contributed to a thrombotic episode.
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Mathis et al. (2008) studied this question.
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