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August 1, 2018BMJ Paediatrics OpenOpen Access

Anxiety in children attending a specialist inherited cardiac arrhythmia clinic: a questionnaire study

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Key result

Inherited cardiac arrhythmia syndromes in children are linked to higher cardiac-focused anxiety scores versus controls.

  • MD 0.32
  • 95% CI 0.11-0.54
  • P=0.003
  • n=200

Why the study?

Are there differences in total and cardiac-focused anxiety levels among children with inherited cardiac arrhythmia syndromes, those with a family history, and healthy controls?

Population

200 children aged 8 to 16 years, comprising 47 with an inherited cardiac arrhythmia syndrome, 78 being…

Design

Cross-sectional

Authors

ALAnna Natalia LastJEJennifer EnglishNationwide Children's HospitalHPHelen PoteUniversity of London

Discussion

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Overview

CAQ shows promise for assessing anxiety in children with inherited arrhythmia syndromes; leaves open need for validation before clinical adoption.

Study Design

Type

Cross-Sectional (n=200)

Multicenter

No

Structured PICO

Are there differences in total and cardiac-focused anxiety levels among children with inherited cardiac arrhythmia syndromes, those with a family history, and healthy controls?

P
Population
200 children aged 8 to 16 years, including 47 with an inherited cardiac arrhythmia syndrome, 78 with a family history, and 75 healthy controls, assessed for cardiac-focused anxiety.
C
Comparator
Control children and children with a family history of inherited cardiac arrhythmia syndrome
O
Outcome
Psychometric performance of the Cardiac Anxiety Questionnaire for Children (CAQ-C) and levels of total and cardiac-focused anxietypatient reported

Main Result

Mean Difference: 0.32 (95% CI 0.11–0.54)

Absolute Event Rate: 1.24% vs 0.92%

p-value: p=0.003

Children attending specialist inherited cardiac arrhythmia clinics exhibit significant differences in cardiac-focused anxiety, highlighting the need for routine psychological screening and targeted intervention.

Limitations

  • Preliminary examination of the psychometric properties of the CAQ-C, requiring further validation of retest reliability and clinical cut-offs.
  • Small sample size for the inherited cardiac arrhythmia syndrome group, leading to a slightly underpowered analysis.
  • Heterogeneity of the inherited cardiac arrhythmia syndromes included.
  • Low recruitment rate (31%) for the control group, potentially introducing selection bias.

Cite This Study

Last et al. (2018) conducted a cross-sectional in Inherited cardiac arrhythmia syndrome (n=200). Inherited cardiac arrhythmia syndrome vs. Healthy control children was evaluated on Total cardiac-focused anxiety score on the Cardiac Anxiety Questionnaire for Children (CAQ-C) (MD 0.32, 95% CI 0.11-0.54, p=0.003). Children with an inherited cardiac arrhythmia syndrome had significantly higher cardiac-focused anxiety scores compared to healthy controls (mean difference 0.32, p=0.003).

synapsesocial.com/papers/6aa172de23c04e973172df5ahttps://doi.org/10.1136/bmjpo-2018-000271
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