The Role of N terminal pro-BNP in assessing severity of Coronary Artery Disease: a prospective study

BNP is a peptide consisting of 2 aminoacids produced by the myocytes as a prohormone .it is released as a response to ventricular dilatation and pressure overload in its active form after peptidases degradation, into the cardiovascular system.BNP levels are increased after myocardial infarction and high levels are related to increased risk of adverse events.Acute coronary syndromes without ST elevation encompass a wide range of events and have different prognostic values in relation to the type of plaque lesions and diffusion of coronary atherosclerosis.The risk assessment, based on clinical history and examination, ECG changes and markers of myocardial damage, still remains relatively inaccurate.So this study was planned to better assess the role of NT pro BNP in assessing severity of CAD in real world practice in a prospective manner with well defined patient inclusion and exclusion among a spectrum of NSTEACS CAD, BNP, ST elevation, NT pro BNP and Angiographic lesions