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February 1, 2000Journal of Nuclear CardiologyOpen Access

Cardiotoxicity of doxorubicin and other anthracycline derivatives

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Key result

Radionuclide LVEF monitoring during doxorubicin therapy remains essential to reduce CHF incidence and severity.

Design

Review

Authors

DJDiwakar JainCardiac Imaging

Discussion

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Implication

Supports LVEF monitoring by radionuclide angiocardiography during doxorubicin; confirms prior recommendations but leaves open refinements with emerging cardioprotective strategies.

PICO

P
Population
Doxorubicin cardiotoxicity
E
Exposure / Comparator
Doxorubicin and other anthracycline derivatives

Current guidelines for LVEF monitoring using equilibrium radionuclide angiocardiography should be followed during doxorubicin therapy to reduce the incidence and severity of congestive heart failure.

Cite This Study

Diwakar Jain (2000) conducted a review in Doxorubicin cardiotoxicity. Doxorubicin and other anthracycline derivatives was evaluated. Careful monitoring of left ventricular ejection fraction with radionuclide angiocardiography during doxorubicin therapy remains essential to reduce the incidence and severity of congestive heart failure.

synapsesocial.com/papers/6aa17a5a43a8dfb51a842dbbhttps://doi.org/10.1067/mnc.2000.103324
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiomyopathy of Doxorubicin in Experimental Animals. Factors Affecting the Severity, Distribution and Evolution of Myocardial Lesions1981 · 65 citations
  2. 2Reduction of Doxorubicin Cardiotoxicity by Prolonged Continuous Intravenous Infusion1982 · 768 citations
  3. 3Probucol Protects Against Adriamycin Cardiomyopathy Without Interfering With Its Antitumor Effect1995 · 286 citations