Key result
Analysis of 36 human heart biopsies showed that sex and age had no significant influence on phospholipid class distribution, with notable species differences compared to rat data.
Population
36 human heart biopsy specimens collected during open heart surgery from patients (mainly aged 40-70)
Design
Other
Authors
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Human cardiac phospholipid profiles show no sex/age effects; leaves open species-specific translation from rodent models.
Observational (n=36)
This study details the baseline phospholipid and fatty acid composition of the human heart, noting species-specific differences compared to rats.
Rocquelin et al. (1989) conducted an observational in Patients undergoing open heart surgery (n=36). Human heart tissue vs. Rat heart tissue was evaluated on Phospholipid content and fatty acid composition. Analysis of 36 human heart biopsies showed that sex and age had no significant influence on phospholipid class distribution, with notable species differences compared to rat data.
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