Key result
Renal replacement therapy successfully managed severe refractory metabolic acidosis and acute kidney injury in a young girl with diabetic ketoacidosis.
Why the study?
Most children with diabetic ketoacidosis respond to standard supportive therapy and fluid resuscitation, but cases with severe refractory metabolic acidosis and acute kidney injury requiring renal replacement therapy are rare.
Case Report (n=1)
Renal replacement therapy can be successfully used to manage severe refractory metabolic acidosis and acute kidney injury in pediatric patients with diabetic ketoacidosis.
May warrant consideration of renal replacement therapy in refractory pediatric DKA; leaves open need for prospective studies on indications and outcomes.
Diabetic ketoacidosis (DKA) is the most serious complication of type I diabetes mellitus (DM) in children.Majority of these patients respond to fluid resuscitation, insulin, and supportive measures and rarely require renal replacement therapy.Here, we report the case of a young girl with DKA with severe refractory metabolic acidosis and acute kidney injury (AKI) and was successfully managed with renal replacement therapy.
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Jain et al. (2020) conducted a case report in Diabetic ketoacidosis with severe refractory metabolic acidosis and acute kidney injury (n=1). Renal replacement therapy was evaluated. Renal replacement therapy successfully managed severe refractory metabolic acidosis and acute kidney injury in a young girl with diabetic ketoacidosis.
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