Key result
Metabolic syndrome, not obesity, linked to higher CVD prevalence in postmenopausal women.
Why the study?
Combined effects of metabolic abnormalities and obesity needed to be identified to screen postmenopausal women at risk of developing cardiovascular diseases.
Does the combination of metabolic syndrome and obesity increase the prevalence of cardiovascular diseases in postmenopausal Korean women?
Cross-Sectional (n=5,959)
Does the combination of metabolic syndrome and obesity increase the prevalence of cardiovascular diseases in postmenopausal Korean women?
In postmenopausal Korean women, metabolic syndrome is more strongly associated with cardiovascular disease prevalence than obesity alone, highlighting the importance of managing metabolic abnormalities over simple weight control.
Metabolic syndrome screening may aid CVD risk identification in postmenopausal women; leaves open obesity's independent contribution beyond multiple abnormalities.
Combined effects of metabolic abnormalities, including metabolic syndrome and obesity, should be identified to screen postmenopausal women at risk of developing cardiovascular diseases. The purpose of this study was to identify the combined effects of metabolic abnormalities and obesity on cardiovascular diseases among postmenopausal Korean women (aged 40–83 years). Data of 5959 postmenopausal women from the Korean National Health and Nutrition Examination Survey (2015–2018) were secondarily analyzed. Using complex simple analysis procedures, logistic regression analysis was performed to identify the combined effect of metabolic abnormalities and obesity on cardiovascular diseases among postmenopausal Korean women. In combination, metabolic syndrome (more than three metabolic abnormalities) and obesity (overweight [≥23 kg/m2 and <25 kg/m2 in body mass index] and obese [>25 kg/m2 in body mass index]) increased the likelihood of developing cardiovascular diseases but combining more than one metabolic abnormality and obesity did not. Combining metabolic syndrome and non-obesity (underweight and normal weight) increased the likelihood of the prevalence of cardiovascular diseases but combining more than one metabolic abnormality and non-obesity did not. Increased cardiovascular diseases in postmenopausal women may be more commonly associated with metabolic syndrome having multiple metabolic abnormalities, but not obesity. Thus, instead of simple weight control, early management of metabolic syndrome is recommended to prevent cardiovascular disease among postmenopausal Korean women.
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Jin Suk (2021) conducted a cross-sectional in Cardiovascular diseases (n=5,959). Metabolic syndrome and obesity vs. Absence of metabolic syndrome or obesity was evaluated on Prevalence of cardiovascular diseases. Metabolic syndrome, rather than obesity, was associated with an increased likelihood of cardiovascular diseases among postmenopausal Korean women.
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