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Expression of an increasing number of eukaryotic genes is known to be regulated through mRNA stability. One of the most interesting examples is the autoregulated instability of tubulin mRNAs, which are destabilized by a novel mechanism involving co-translational binding of their own mature translation products (tubulin subunits) to the nascent tubulin polypeptide just after it emerges from the ribosome.
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Don W. Cleveland (1988) studied this question.
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