Key result
Individualized stepwise lung recruitment maneuvers reduce postoperative pulmonary complications versus control.
Why the study?
Recruitment maneuvers as part of lung-protective ventilation may improve lung mechanics and oxygenation, but definitive guidelines for their intraoperative application have not been established.
Does individualized stepwise lung recruitment maneuver reduce postoperative pulmonary complications in patients undergoing non-laparoscopic upper abdominal surgeries under general anesthesia?
RCT (n=66)
Single-blind
Does individualized stepwise lung recruitment maneuver reduce postoperative pulmonary complications in patients undergoing non-laparoscopic upper abdominal surgeries under general anesthesia?
Individualized stepwise lung recruitment maneuvers added to lung protective ventilation significantly decrease postoperative pulmonary complications in patients undergoing non-laparoscopic upper abdominal surgeries.
Answers are grounded in this paper and cite their sources.
Supports individualized recruitment with lung-protective ventilation in upper abdominal surgery; extends evidence to non-laparoscopic procedures.
Background The concept of lung protective ventilation (LPV) during general anesthesia (GA) aims at minimizing lung injury and postoperative pulmonary complications (POPCs). Recruitment maneuver (RM) as a part of LPV may improve lung mechanics and oxygenation, but despite extensive research, definitive guidelines for the applications of intraoperative RMs have not been established yet.Methods This study was a prospective, single-blinded, randomized clinical trial. Sixty-six subjects undergoing non-laparoscopic upper abdominal surgeries under GA were randomly assigned into two equal groups. Control group (C) received tidal volume of 8 ml/kg predicted body weight (PBW) and positive end expiratory pressure (PEEP) of 5 cmH2O without RM. Recruitment group (R) received tidal volume of 8 ml/kg PBW with stepwise RMs and individualized PEEP titration after each RM. Compliance, plateau pressure, driving pressure, SpO2 and hemodynamics were monitored at each step of RM. POPCs, length of hospital stay and mortality were recorded postoperatively.Results There was a significant reduction in POPCs in (R) group than in (C) group (P = 0.03). Also, there was a significant increase in compliance before extubation in (R) group (P = 0.001). However, no significant difference was noted between both groups as regards mortality rate and length of hospital stay.Conclusion Individualized stepwise lung RM significantly decreases the incidence of POPCs when added to LPV in patients undergoing non-laparoscopic upper abdominal surgeries under GA.
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Salama et al. (2023) conducted an RCT in Non-laparoscopic upper abdominal surgeries under general anesthesia (n=66). Individualized stepwise lung recruitment maneuvers (RM) and PEEP titration vs. Tidal volume of 8 ml/kg PBW and PEEP of 5 cmH2O without RM was evaluated on Postoperative pulmonary complications (POPCs) (p=0.03). Individualized stepwise lung recruitment maneuvers decreased the incidence of postoperative pulmonary complications compared to control.
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