Obesity, insulin resistance, and hormonal perturbations in Iraqi women

Background: Obesity and increased weight are related to Polycystic Ovarian Syndrome (PCOS) progression and exacerbate Insulin Resistance (IR). Aims of the study: This research aimed to assess the potential impacts of BMI and IR on the functions of the pituitary-ovary and the pituitary-thyroid axis by assessing the Follicle-Stimulating Hormone (FSH), Estradiol (E2), Luteinizing Hormone (LH), Thyroid Stimulating Hormone (TSH), Triiodothyronine (T3), Thyroxine (T4) and prolactin serum levels in the overweight and the obese PCOS groups. Methodology: From May to December 2023, Martyr Mohammed Baqer Al-Hakim Hospital in Baghdad City, Iraq, conducted this prospective study. The individuals were divided into three BMI groups: 40 in the normal weight control group (BMI