Key result
Inoue balloon PTMC expands mitral valve area by ~1 cm2 in pediatric patients.
Why the study?
Is percutaneous transvenous mitral commissurotomy using the Inoue balloon safe and effective in children less than 12 years with severe rheumatic mitral stenosis?
Population
45 children with severe rheumatic mitral stenosis
Comparison
Percutaneous transvenous mitral commissurotomy… vs Maximum balloon size same as recommended by…
Design
Cohort
Follow-up
20.4 +/- 16.3 months (range 3-56 months)
Authors
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Supports short-term hemodynamic gains with Inoue PTMC in children <12 years; leaves open need for randomized trials on durability and optimal sizing.
Cohort (n=45)
Is percutaneous transvenous mitral commissurotomy using the Inoue balloon safe and effective in children less than 12 years with severe rheumatic mitral stenosis?
Absolute Event Rate: 1.63% vs 0.64%
p-value: p=<0.0001
PTMC using the Inoue balloon is safe and effective for severe rheumatic mitral stenosis in children under 12, and using a balloon size 1-3 mm smaller than recommended by height yields comparable efficacy.
Kothari et al. (1998) conducted a cohort in Severe rheumatic mitral stenosis (n=45). Percutaneous transvenous mitral commissurotomy (PTMC) using Inoue balloon vs. Baseline was evaluated on Mitral valve area (cm2) (p=<0.0001). Percutaneous transvenous mitral commissurotomy using the Inoue balloon significantly increased mitral valve area from 0.64 to 1.63 cm2 (P<0.0001) in children under 12 years.
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