Key result
Serial echo during adriamycin therapy detects LV deterioration, allowing therapy modifications to minimize fatal HF.
Why the study?
Does serial echocardiography detect left ventricular function deterioration in patients receiving adriamycin for osteogenic sarcoma?
Observational (n=26)
Does serial echocardiography detect left ventricular function deterioration in patients receiving adriamycin for osteogenic sarcoma?
Serial echocardiography is a valuable tool for monitoring adriamycin-induced cardiotoxicity, allowing for timely withholding of therapy to prevent fatal congestive heart failure.
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May support serial echocardiography for adriamycin cardiotoxicity monitoring to limit HF; hypothesis-generating and requires randomized confirmation.
Bloom et al. (1978) conducted an observational in Osteogenic sarcoma (n=26). Adriamycin was evaluated on Left ventricular function deterioration. Serial echocardiographic assessments in patients receiving adriamycin detected significant left ventricular function deterioration, allowing therapy modification and limiting fatal heart failure to 1 case.
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