Key result
Analysis of porcine plasma revealed significant amounts of galactosylceramide and digalactosylceramide, with 55-80% of glycosphingolipids distributed between the d 1.020-1.060 and d 1.090-1.210 g/mL fractions.
The study identifies significant intrinsic variability in porcine plasma glycosphingolipids and highlights differences in their lipoprotein distribution compared to humans, which is relevant when using swine as atherosclerosis models.
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Porcine glycosphingolipid distribution differs from humans; leaves open swine suitability as models for human lipoprotein metabolism in atherosclerosis.
Clarke et al. (1979) studied this question. Extraction and analysis of neutral glycosphingolipids vs. Human plasma was evaluated on Composition and distribution of neutral glycosphingolipids in porcine plasma lipoproteins. Analysis of porcine plasma revealed significant amounts of galactosylceramide and digalactosylceramide, with 55-80% of glycosphingolipids distributed between the d 1.020-1.060 and d 1.090-1.210 g/mL fractions.
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