Key result
SYNTAX Score II was significantly higher in patients with carotid artery disease compared to those without (28.4 vs 21.4; P<0.001) and independently predicted disease presence and severity.
Why the study?
Given the known association between coronary artery disease and carotid artery disease, the authors investigated the association between the presence and severity of carotid artery disease and the SYNTAX score and SYNTAX score II in patients undergoing CABG.
Is the SYNTAX score II associated with the presence and severity of carotid artery disease in patients undergoing coronary artery bypass grafting?
Observational (n=287)
Is the SYNTAX score II associated with the presence and severity of carotid artery disease in patients undergoing coronary artery bypass grafting?
The SYNTAX score II is an independent predictor of the presence and severity of carotid artery disease in patients undergoing CABG.
May inform carotid screening in CABG patients; hypothesis-generating and requires prospective validation.
The SYNTAX score (SS) and SS II, which include additional clinical parameters, are widely used today for deciding revascularization following coronary angiography. We investigated the association between the presence and severity of carotid artery disease (CrAD) using the SS and SS II in 287 patients who underwent coronary artery bypass grafting. We based this investigation on the known association between coronary artery disease and CrAD. A significant association was observed between the groups with and without CrAD in terms of SS II values (28.4 ± 9.6 vs 21.4 ± 7.7, respectively; P < .001). A significant difference was also observed when stenosis was classified according to severity as <50%, 50% to 70%, and >70% ( P < .001). The results indicated a positive correlation between the presence and severity of CrAD as SS II increased ( r = 0.187, P = .005). According to the results of multivariate logistic regression analysis, the SS II was an independent predictor of CrAD.
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Ermiş et al. (2019) conducted an observational in Coronary artery disease requiring coronary artery bypass grafting (n=287). SYNTAX Score II was evaluated on Presence of carotid artery disease (CrAD) (p=<.001). SYNTAX Score II was significantly higher in patients with carotid artery disease compared to those without (28.4 vs 21.4; P<0.001) and independently predicted disease presence and severity.
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