Key result
Higher mean platelet volume and age were identified as independent predictors of acute myocardial infarction in young patients.
Why the study?
Does mean platelet volume predict acute myocardial infarction in young patients?
Observational (n=514)
No
Does mean platelet volume predict acute myocardial infarction in young patients?
Mean platelet volume is an independent predictor of acute myocardial infarction in young patients.
Should not yet guide risk assessment in young patients; hypothesis-generating for MPV in AMI prediction.
Increased mean platelet volume (MPV) is associated with poor clinical outcome in patients with acute coronary syndrome. We evaluated the predictive role of MPV in young patients with acute myocardial infarction (AMI). This study includes 373 patients who presented to our hospital with AMI (group 1: 134 young patients, males aged <45 years and females aged <55 years; group 2: 239 older patients) and 141 adults with normal coronary angiography as a control group (group 3). In group 1, the levels of MPV and hemoglobin were higher than that in groups 2 and 3. In group 1, blood urea nitrogen levels were lower than that in groups 2 and 3 and creatinine levels were lower than that in group 2. After multivariate analysis, MPV and age were independent predictors of AMI in young patients.
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Özkan et al. (2012) conducted an observational in Acute myocardial infarction (n=514). Mean platelet volume vs. Older AMI patients and normal coronary angiography controls was evaluated on Predictors of acute myocardial infarction in young patients. Higher mean platelet volume and age were identified as independent predictors of acute myocardial infarction in young patients.
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