Key result
Higher carotid Plaque-RADS scores were significantly associated with cerebrovascular events (OR 1.11 per 1-level increase; 95% CI 1.01-1.24; p=0.04).
Why the study?
The study aimed to evaluate carotid Plaque-RADS and its relationship with clinical risk factors and ipsilateral cerebrovascular symptoms using a prospective, multicenter vessel-wall MRI dataset.
Does Carotid Plaque-RADS evaluation using multiple contrast vessel wall MRI associate with ipsilateral cerebrovascular events in symptomatic patients with recent stroke or transient ischemia attack?
Cross-Sectional (n=433)
Yes
Does Carotid Plaque-RADS evaluation using multiple contrast vessel wall MRI associate with ipsilateral cerebrovascular events in symptomatic patients with recent stroke or transient ischemia attack?
Odds Ratio: 1.11 (95% CI 1.01–1.24)
p-value: p=0.04
Plaque-RADS can stratify patients experiencing cerebrovascular events even with mild-to-moderate stenosis, though its independent predictive value is attenuated when adjusting for stenosis severity or plaque burden.
Should not yet change carotid imaging practice; leaves open whether Plaque RADS adds value beyond stenosis or plaque burden.
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Wang et al. (2025) conducted a cross-sectional in Recent stroke or transient ischemia attack with carotid atherosclerotic plaques (n=433). Carotid Plaque-RADS score was evaluated on Cerebrovascular events (OR 1.11, 95% CI 1.01-1.24, p=0.04). Higher carotid Plaque-RADS scores were significantly associated with cerebrovascular events (OR 1.11 per 1-level increase; 95% CI 1.01-1.24; p=0.04).
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