Key result
In AMI shock, LVEDP consistently measures at least ~2x RAP.
Observational (n=18)
In patients with shock due to acute myocardial infarction, left ventricular filling pressures are significantly higher than right-sided pressures, suggesting central venous pressure is an inadequate index of left ventricular function.
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Central venous pressure may underestimate LV filling in AMI shock; leaves open whether targeted LVEDP monitoring improves outcomes today.
s1 May 1968Left and Right Ventricular Filling Pressures in Clinical Shock.Jay N. Cohn, M.D., F.A.C.P., Ibrahim M. Khatri, M.D., Felix E. Tristani, M.D.Jay N. Cohn, M.D., F.A.C.P., Ibrahim M. Khatri, M.D., Felix E. Tristani, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-68-5-1153_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptCentral venous pressure is used clinically as an index of myocardial function in shock, but the relationship between right and left heart filling pressures in this situation has not been analyzed. Simultaneous measurements of right atrial (RAP) and left ventricular end diastolic (LVEDP) pressures were performed at the bedside of 18 patients with shock (9, acute myocardial infarction; 6, sepsis; 2, pulmonary embolism; 1, hepatic failure).In acute myocardial infarction LVEDP ranged from 14 to 30 mm Hg (average, 21 mm Hg) and was always at least twice the RAP (range, 3 to 14 mm Hg, average, 8.7 mm Hg).... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Washington, D. C. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByLeft Ventricular Function in Acute Myocardial Infarction and its Clinical SignificanceLeft ventricular failure in acute myocardial infarctionHypovolemia in Shock Due to Acute Myocardial Infarction 1 May 1968Volume 68, Issue 5Page: 1153-1153KeywordsAcute myocardial infarctionHeartPatient advocacyPulmonary embolismSepsisShock Issue Published: 1 May 1968 PDF DownloadLoading ...
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Jay N. Cohn (1968) conducted an observational in Clinical shock (n=18). Simultaneous measurement of right atrial and left ventricular end diastolic pressures was evaluated on Relationship between right atrial (RAP) and left ventricular end diastolic (LVEDP) pressures. In patients with shock due to acute myocardial infarction, left ventricular end diastolic pressure averaged 21 mm Hg and was always at least twice the right atrial pressure.
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