Pulmonary microvascular metastases in cervical carcinoma

Figures

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  Figure 1. Case 1 - (a) Normal cut surface of the right lung; the histology revealed clusters of tumor cells without; (b) or with admixed fibrin; (c) Pulmonary microvascular tumor embolism (H&E × 400); (d) The tumor cells were positive for cytokeratin 7 (×400)

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  Figure 2. Case 2 - (a) Muscular pulmonary artery occluded by fresh thrombus with peripheral organization and strands of tumor (arrows); (b) Recanalized thrombus in a muscular pulmonary artery. The channels themselves are occluded by tumor clusters. Note the presence of lymphatic permeation; (c) Portal tract of the liver showing occlusive tumor embolus in the portal vein radicles V; (d) The sinusoids of the liver were focally dilated and some show the presence of tumor cells (H&E × 100)

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  Figure 3. Case 4 - Abdominal CT - (a) Multiple homogeneously enhancing retroperitoneal lymph nodes (circled area) ranging from 2 cm to 2.5 cm, encasing the ureters. This has led to bilateral hydronephrosis. Note the presence of urinoma (U, arrow) over right kidney RK, 2 cm thick with a flap of tissue within (LK left kidney, P pelvis); (b) At the pelvic region, there was thickening of lower uterine segment extending into the pouches of Douglas. Encircled are the inguinal lymphadenopathies; (c) Cob-web like network of gray-white streaks was present over the visceral pleura of unfixed lung

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  Figure 4. Case 4 - (a) The cut surface of the right lung shows gray-white prominence of the lobular septa and bronchovascular connective tissues with occlusive, fresh arterial thrombus (arrow) and metastatic infiltration of hilar lymph nodes; the lymphatics around muscular artery is plugged by tumor emboli as seen on (b) Hematoxylin and eosin and (c) elastic van Gieson stained slides (×100)