Key result
LH-RH analogues and antiandrogens completely clear pulmonary lymphangitic carcinomatosis in prostate cancer.
Pulmonary lymphangitic carcinomatosis can be the initial presentation of prostate cancer and may respond completely to androgen deprivation therapy.
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Supports rare metastatic presentations for hormonal therapy; leaves open generalizability pending prospective data.
Lymphangitic carcinomatosis of the lung is a late and often fatal manifestation of cancer. We describe a case of a biopsy-proved pulmonary lymphangitic carcinomatosis in an asymptomatic 61-year-old man. The pulmonary picture proved to be the initial sign of a prostatic cancer. Therapy with LH-RH analogues and antiandrogens achieved a complete clearance of lung involvement.
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Miseria et al. (1991) studied this question. Therapy with LH-RH analogues and antiandrogens achieved complete clearance of pulmonary lymphangitic carcinomatosis that presented as the initial sign of prostate cancer.
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