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December 8, 2025Cancer Treatment and Research CommunicationsOpen Access

The burden of bladder cancer in the MENA region: a 3-decade analysis

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Authors

SSSaeid SafiriKHKamaleddin HassanzadehASAli Shamekh

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Overview

Epidemiological analysis reveals stable overall bladder cancer burden across the Middle East and North Africa from 1990 to 2021, highlighting the need for targeted regional prevention strategies.

Key Points

  • Assess the 30-year epidemiological burden and regional trends of bladder cancer across the Middle East and North Africa using Global Burden of Disease 2021 data.
  • Extracted incidence, mortality, and disability-adjusted life years (DALYs) attributable to bladder cancer across the region from 1990 to 2021.
  • Calculated total counts and age-standardized rates with corresponding 95% uncertainty intervals (UIs) across individual countries.
  • In 2021, regional age-standardized incidence was 8.2 per 100,000 (95% UI: 6.9 to 10.0), mortality was 3.2 per 100,000 (95% UI: 2.8% to 3.9%), and the DALY rate was 66.3 per 100,000 (95% UI: 13.9 to 24.9), with no statistically significant changes since 1990.
  • Country-specific trajectories diverged sharply: Iraq, Kuwait, and Iran experienced significant increases in age-standardized incidence rates, whereas Qatar and Bahrain achieved significant decreases in mortality and DALY rates.

Cite This Study

Safiri et al. (2025) studied this question.

synapsesocial.com/papers/6aa261fec1342f4f607f6033https://doi.org/10.1016/j.ctarc.2025.101066
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