Key result
Aminophylline linked to fewer syncopal episodes in a dog with paroxysmal AV block.
Why the study?
There is little information on paroxysmal atrioventricular blocks in dogs, where further electrocardiographic event characterisation may influence therapy choices.
Does aminophylline reduce syncopal episodes in a dog with paroxysmal atrioventricular block?
Case Report (n=1)
Does aminophylline reduce syncopal episodes in a dog with paroxysmal atrioventricular block?
Aminophylline may be effective in reducing syncopal episodes associated with paroxysmal atrioventricular block in dogs.
Documents paroxysmal AV block during syncope in one dog; hypothesis-generating and requires prospective validation before clinical adoption.
An 11‐year‐old female mixed‐breed dog was presented with syncopal episodes occurring up to 10 times a day for 3 months. The owner reported events lasting for approximately 15 s, during which the dog would fall into lateral recumbency, have muscle tremors and show intense salivation. After the event, the animal was disorientated for a few seconds before full recovery. A surface electrocardiogram was obtained, during which an episode of syncope occurred, with a paroxysmal atrioventricular block lasting 10.5 s. The event was characterised as an intrinsic pause‐dependent paroxysmal atrioventricular block associated with cardiogenic syncope type 1E. The dog received aminophylline 10 mg/kg every 8 hours and the frequency of syncopal episodes decreased until it died of non‐cardiac causes 3 months later. There is little information on paroxysmal atrioventricular blocks in dogs, and further electrocardiographic event characterisation may the influence choice of therapy in individual cases.
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Pessoa et al. (2023) conducted a case report in Paroxysmal atrioventricular block (n=1). Aminophylline was evaluated on Frequency of syncopal episodes. Aminophylline (10 mg/kg every 8 hours) decreased the frequency of syncopal episodes in a dog with paroxysmal atrioventricular block until death from non-cardiac causes 3 months later.
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