Applications of 1‐alkoxycarbonyl‐ and 1‐acyl‐v‐triazolo[4,5‐b]pyridines as acylating reagents

Selective N‐protection of hydroxyamino esters has been readily achieved using 1‐alkoxycarbonyl‐ or 1‐acyl‐v‐triazolo[4,5‐b]pyridines. The amide‐type triazolides reacted with alcohols in the presence of DBU at room temperature to afford in high yields the corresponding esters. The different reactivity of 1‐ and 3‐alkoxycarbonyl derivatives of the title bicyclic system toward primary amines has been further investigated.