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The National Institutes of Health played no role in the preparation of this essay.JL declares that she has pending patent applications on the use of RNA interference to target HIV infection or fas and other apoptotic or proinfl ammatory genes activated in response to infection; on the topical application of small interfering RNAs for use as a microbicide or for other antiviral prevention or treatment indications; and on cell-type-specifi c small interfering RNA delivery using an antibody fragment-protamine fusion protein.
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Dykxhoorn et al. (2006) studied this question.
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