Key result
This review describes various percutaneous therapeutic options available for the treatment of tricuspid insufficiency in patients at very high surgical risk or who are inoperable.
Why the study?
Surgical treatment for tricuspid insufficiency is limited by high in-hospital mortality and comorbidities, prompting the need to describe emerging percutaneous therapeutic options for very high-risk or inoperable patients.
This review highlights emerging percutaneous therapeutic options for tricuspid insufficiency in high-risk or inoperable patients.
May expand options for inoperable tricuspid regurgitation; leaves open randomized validation of safety and durability.
The renewed interest in tricuspid valve pathology is a consequence of the high mortality rate associated with this valve dysfunction, mostly functional, and secondary to left ventricular impairment, or pulmonary hypertension. Despite the clear relationship between tricuspid insufficiency and mortality, surgical treatment is offered to a small group of patients, due to the significant in-hospital mortality secondary also to the multiple comorbidities and the advanced stage of left ventricular dysfunction. During the last few years, new therapeutic options have been developed for the percutaneous treatment of tricuspid insufficiency which, albeit still in the experimental phase, provides an alternative to surgery in patients at very high-risk or frankly inoperable. We will describe the various percutaneous therapeutic options available today, and their potential application to clinical practice.
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Giannini et al. (2019) conducted a review in Tricuspid insufficiency and refractory right heart failure. Percutaneous treatment of tricuspid valve was evaluated. This review describes various percutaneous therapeutic options available for the treatment of tricuspid insufficiency in patients at very high surgical risk or who are inoperable.
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