Key result
Tbx18 is expressed in murine cardiomyocytes from E10.5 to at least E14.5, whereas Wt1 is expressed within the heart from E12.5 to at least E14.5 but not in cardiomyocytes.
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Should not guide clinical decisions in congenital heart disease; leaves open functional roles of Tbx18 and Wt1 in cardiogenesis.
Zeng et al. (2011) studied Embryonic heart development (n=8). Immunofluorescence staining for Tbx18 and Wt1 was evaluated on Expression and colocalization of Tbx18 and Wt1 with Nkx2.5. Tbx18 is expressed in murine cardiomyocytes from E10.5 to at least E14.5, whereas Wt1 is expressed within the heart from E12.5 to at least E14.5 but not in cardiomyocytes.
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