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September 10, 2026BMC BiologyOpen Access

Group II Mcr-encoding archaea exhibit methane-cycling potential in geothermal springs

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Authors

XCXiao-Xi ChenYQYan-Ni QuYLYu-Xian Li

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Overview

Metagenomic analysis reveals active Group II Mcr-encoding archaea in terrestrial geothermal springs, indicating non-euryarchaeal lineages play key roles in global methane cycling.

Key Points

  • To investigate the distribution, ecological roles, and evolutionary history of methyl-coenzyme M reductase (Mcr)-encoding archaea in terrestrial geothermal springs.
  • Performed metagenomic sequencing of 157 terrestrial geothermal springs in Tengchong, China.
  • Reconstructed and annotated 104 Mcr-containing metagenome-assembled genomes (MAGs).
  • Conducted metatranscriptomic profiling and phylogenetic analyses across varying temperature and pH regimes.
  • Reconstructed 90 Group II Mcr-encoding MAGs, predominantly Methanosuratincolia, which exceeded Group I euryarchaeotal MAGs in relative abundance across most spring samples.
  • Detected elevated transcriptional activity of methane-metabolism genes under extreme thermal (> 70 °C) and alkaline (pH > 9) conditions.
  • Identified hydrogenotrophic and heterotrophic pathways in Bathyarchaeia MAGs along with evidence of horizontal gene transfer with Methanonezhaarchaeia, supporting methylotrophic methanogenesis as ancestral among sampled Mcr-containing Thermoproteota.

Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6aa27ae958559d80afc73c2ehttps://doi.org/10.1186/s12915-026-02727-z
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