Key result
Protocol-based BP management is linked to improved mean blood pressure and BP control versus baseline.
Why the study?
Blood pressure control remains suboptimal worldwide due partly to poor guideline implementation, and data on the efficacy of protocol-based BP management are sparse in South Asia.
Does protocol-based blood pressure management improve blood pressure control in outpatients?
Cohort (n=13,097)
Yes
Does protocol-based blood pressure management improve blood pressure control in outpatients?
Protocol-based blood pressure management significantly improves blood pressure control in outpatient settings, particularly in primary healthcare facilities.
Associated with improved outpatient BP control; hypothesis-generating and requires RCTs before practice change.
Despite established guidelines, blood pressure(BP) control remains suboptimal worldwide. Poor implementation of guidelines is identified as a contributing factor. “Protocol-based BP management(PB-BPM)” is a suggested solution and has been implemented in Sri Lanka. However, data on the efficacy of PB-BPM are sparse in South Asia. We assessed the efficacy of PB-BPM in the outpatient clinics of the primary and secondary/tertiary healthcare facilities in Sri Lanka by analysing BP data of those with 6 or more months’ follow-up by 31 st December 2025. Controlled BP was defined as <140/90 mmHg per the WHO guideline. We compared mean BP and the percentage with controlled BP between baseline and the end of follow-up. BP control of 13097 patients (male 3480(26.6%, mean age 64( ± 10.2) were studied. Mean systolic BP(SBP p < 0.001), diastolic BP(DBP p < 0.001), and the percentage with controlled BP (p < 0.001) improved significantly at follow-up compared to baseline. Mean reduction in SBP/ DBP was more in primary compared to secondary/tertiary care facilities (p < 0.001/ p < 0.001), with high baseline SBP(r = 0.671, p < 0.001) and DBP(r = 0.639, p < 0.001). In conclusion, PB-BPM improved BP control among outpatients managed at state hospitals in Sri Lanka, with greater efficacy observed in primary healthcare facilities and among patients with high baseline BP.
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Mettananda et al. (2026) conducted a cohort in Suboptimal blood pressure control (n=13,097). Protocol-based blood pressure management (PB-BPM) vs. Baseline was evaluated on Mean BP and percentage with controlled BP (<140/90 mmHg) (p=<0.001). Protocol-based blood pressure management significantly improved mean systolic and diastolic blood pressure and the percentage of patients with controlled BP compared to baseline (p<0.001).
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