Key result
Combined low functional capacity and frailty are not linked to postoperative complications after cardiac surgery.
Why the study?
Functional capacity and frailty represent distinct vulnerability dimensions in cardiac surgery patients, but the prognostic value of their combined assessment remains unclear.
Does combined assessment of low functional capacity and frailty predict postoperative complications in adults undergoing elective conventional cardiac surgery?
Cohort (n=68)
No
Does combined assessment of low functional capacity and frailty predict postoperative complications in adults undergoing elective conventional cardiac surgery?
Odds Ratio: 3.95 (95% CI 0.736–21.205)
p-value: p=0.109
Combined assessment of low functional capacity and frailty did not independently predict postoperative complications in a selected cohort undergoing elective cardiac surgery, though it was associated with longer ICU and hospital stays.
Combined screening should not yet guide risk stratification in elective cardiac surgery; leaves open predictive utility in larger cohorts with alternative measures.
Purpose Functional capacity and frailty represent distinct dimensions of vulnerability in patients undergoing cardiac surgery. While functional capacity is objectively measured, frailty reflects a subjective clinical assessment. Despite their association with adverse outcomes, the prognostic value of their combined assessment remains unclear. To evaluate the association of combined low functional capacity and frailty with post-surgical complications in patients undergoing elective cardiac surgery. Methods This prospective study included adults undergoing elective conventional cardiac surgery. Functional capacity and frailty were evaluated using the Short Physical Performance Battery (SPPB) and Clinical Frailty Scale (CFS), respectively, before surgery (M0) and at discharge (M1). To capture both conditions, participants were categorized according impairment, defined as SPPB ≤ 6 and CFS ≥ 4, and by the difference between the two scores (SPPB – CFS). Outcomes included length of stay in intensive care unit (ICU), duration of mechanical ventilation (MV), hospital length of stay (LOS), postoperative complications, and in-hospital mortality. Results Among 68 participants, 20.6% had low functional capacity and 18.8% were pre-frail or frail. The combined prevalence was 17.6%. Functional capacity declined postoperatively ( p < 0.001). The length of hospital stay and ICU stay was longer in individuals who experienced postoperative complications ( p < 0.001). Among those with complications, 66.7% had both conditions. Individuals with complications had a lower subtraction score (5.5 [1.0-7.2] vs. 7 [5.0–9.0]; p = 0.048). However, no significant association remained in adjusted regression models. Conclusion Combined low functional capacity and frailty were not associated with postoperative complications after elective conventional cardiac surgery.
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Cunha et al. (2026) conducted a cohort in Elective conventional cardiac surgery (n=68). Combined low functional capacity and frailty vs. Absence of combined low functional capacity and frailty was evaluated on Post-surgical complications (OR 3.95, 95% CI 0.736-21.205, p=0.109). Combined low functional capacity and frailty were not significantly associated with postoperative complications after elective conventional cardiac surgery in adjusted models.
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