What does this research mean for the field?

Combining dietary weight loss with physical activity strategies, such as aerobic exercise or daylong movement, significantly reduces perceived physical fatigability in older adults with obesity. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the effects of dietary weight loss combined with three different physical activity interventions on perceived physical fatigability in older adults with obesity.

September 10, 2026ObesityOpen Access

Weight Loss and Physical Activity Reduces Perceived Physical Fatigability Among Older Adults With Obesity

View Full Paper

Ask AI

Bookmark

Authors

RGReagan E. GarciaUniversity of Pittsburgh JFJason FanningCenter For Remote Sensing (United States)CKChaeryon KangUniversity of Pittsburgh

Discussion

Member takes

Implication

Randomized trial demonstrates that combining weight loss with exercise reduces perceived physical fatigability in older adults with obesity, highlighting sustained functional benefits.

Key Points

To evaluate the effects of dietary weight loss combined with three different physical activity interventions on perceived physical fatigability in older adults with obesity.
Older adults with obesity (N = 183; ClinicalTrials.gov NCT02923674) underwent a dietary caloric restriction program (~400 kcal/day deficit) and were randomized to aerobic exercise (n = 60), daylong movement (n = 63), or a combination of both (n = 60).
Perceived physical fatigability was measured at baseline, 6 months, and 18 months using the Pittsburgh Fatigability Scale (PFS Physical score) and Rating of Perceived Exertion (RPE) after a 5-minute treadmill walk.
PFS Physical score improved significantly from baseline to 6 months (−4.4 points, p = 0.002) and remained improved at 18 months (−3.0 points, p = 0.03) after adjusting for covariates, with no significant differences across intervention arms (time × group p = 0.83).
Rating of Perceived Exertion fatigability after a 5-minute walk showed no statistically significant change across time points (p > 0.05).

Cite This Study

Garcia et al. (2026) studied this question.

synapsesocial.com/papers/6aa27bfe58559d80afc758b3 https://doi.org/10.1002/oby.70298

View Full Paper

Ask AI

Bookmark

Implication

Randomized trial demonstrates that combining weight loss with exercise reduces perceived physical fatigability in older adults with obesity, highlighting sustained functional benefits.

Weight Loss and Physical Activity Reduces Perceived Physical Fatigability Among Older Adults With Obesity

Discussion

Member takes

Implication

Key Points

Cite This Study

Weight Loss and Physical Activity Reduces Perceived Physical Fatigability Among Older Adults With Obesity

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider