Key result
CHF history linked to ~100% higher odds of postoperative death after elective spine fusion.
Why the study?
There is a paucity of data on the effect of different cardiac diagnoses on outcomes in patients undergoing elective spine fusion.
Does a history of specific cardiac diseases increase the risk of postoperative complications in patients undergoing elective spine fusion surgery?
Cohort (n=537,252)
Does a history of specific cardiac diseases increase the risk of postoperative complications in patients undergoing elective spine fusion surgery?
A history of specific cardiac diseases, particularly congestive heart failure and coronary artery disease, significantly increases the risk of major postoperative complications and mortality following elective spine fusion surgery.
CHF history signals higher postoperative mortality after elective spine fusion; leaves open whether targeted optimization improves outcomes.
INTRODUCTION: There is paucity on the effect of different cardiac diagnoses on outcomes in elective spine fusion patients. METHODS: Patients undergoing elective spine fusion surgery were isolated in the PearlDiver database. Patients were stratified by having a previous history of coronary artery disease (CAD), congestive heart failure (CHF), valve disorder (valve), dysrhythmia, and no heart disease (control). Means comparison tests (chi-squared and independent samples t-tests, as appropriate) compared differences in demographics, diagnoses, comorbidities, procedural characteristics, length of stay, complication outcomes, and total hospital charges among the cohort. RESULTS: In total, 537,252 elective spine fusion patients were stratified into five groups: CAD, CHF, valve, dysrhythmia, and control. Among the cohort, patients with CHF had significantly higher rates of morbid obesity, peripheral vascular disease, and chronic kidney disease (P < 0.001 for all). Patients with CAD had significantly higher rates of chronic obstructive pulmonary disease, diabetes, hypertension, and hyperlipidemia (all P < 0.001). Comparing postoperative outcomes for CAD and control subjects, CAD was associated with higher odds of myocardial infarction (odds ratio [OR]: 1.64 [1.27 to 2.11]) (P < 0.05). Assessing postoperative outcomes for CHF versus control subjects, patients with CHF had higher rates of pneumonia, cerebrovascular accident (CVA), myocardial infarction, sepsis, and death (P < 0.001). Compared with control subjects, CHF was a significant predictor of death in spine fusion patients (OR: 2.0 [1.1 to 3.5], P = 0.022). Patients with valve disorder compared with control displayed significantly higher rates of 30-day readmission (P < 0.05) and 1.38× greater odds of CVA by 90 days postoperatively (OR: 1.4 [1.1 to 1.7], P = 0.007). Patients with dysrhythmia were associated with significantly higher odds of CVA (OR: 1.8 [1.4 to 2.3], P < 0.001) by 30 days postoperatively. CONCLUSION: Heart disease presents an additional challenge to spine fusion patients who are undergoing a challenging and risky procedure. Before surgical intervention, a proper understanding of cardiac diagnoses could give insight into the potential risks for each patient based on their heart condition and preventive measures showing benefit in minimizing perioperative complications after elective spine fusion.
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A 2022 study conducted a cohort in elective spine fusion (n=537,252). Congestive heart failure vs. no heart disease was evaluated on death (OR 2.0, 95% CI 1.1 to 3.5, p=0.022). In patients undergoing elective spine fusion, a history of congestive heart failure significantly increased the odds of postoperative death compared to controls (OR 2.0; 95% CI 1.1-3.5; P=0.022).
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