Key result
Pre-transplant risk score predicts ~136% higher odds of severe adverse events at one year.
Why the study?
Does a pre-transplant risk stratification tool predict severe adverse events at 1 year post-transplant in potential kidney transplant recipients?
Population
495 potential kidney transplant recipients (development cohort N=368, validation cohort N=127)
Design
Cohort
Follow-up
1 year
Authors
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May aid pre-transplant counseling; leaves open whether score-guided interventions improve outcomes.
Cohort (n=495)
Does a pre-transplant risk stratification tool predict severe adverse events at 1 year post-transplant in potential kidney transplant recipients?
Odds Ratio: 2.36
p-value: p=<.001
A simple pre-transplant scoring system using clinical characteristics can effectively stratify potential kidney transplant recipients for risk of severe adverse events at 1 year.
Nygaard et al. (2016) conducted a cohort in Potential kidney transplant recipients (n=495). Pre-transplant risk stratification score vs. Average-risk patients was evaluated on Severe adverse events 1 year post-transplant (OR 2.36, p=<.001). A pre-transplant risk stratification score demonstrated good discrimination (C statistic 0.74) and strongly predicted severe adverse events at 1 year post-transplant (OR 2.36, P<0.001).
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