Why the study?
Does atrial fibrillation detected after stroke (AFDAS) have a different risk of ischemic stroke recurrence compared to known AF when adjusting for prior oral anticoagulation?
Design
Editorial
Key result
Adjusting for pre-stroke oral anticoagulation eliminated the higher hazard for ischemic stroke recurrence previously associated with known atrial fibrillation compared to post-stroke detected AF.
Authors
Loading...
Pre-stroke anticoagulation explains apparent AF-type differences in recurrence; leaves open independent effects of detection timing and requires prospective validation.
Does atrial fibrillation detected after stroke (AFDAS) have a different risk of ischemic stroke recurrence compared to known AF when adjusting for prior oral anticoagulation?
The apparent higher stroke recurrence risk in known AF compared to AF detected after stroke is likely confounded by pre-stroke oral anticoagulation and higher prevalence of vascular risk factors, suggesting both entities warrant similar secondary prevention strategies.
Yaghi et al. (2023) conducted an editorial in Acute ischemic stroke and atrial fibrillation. Atrial fibrillation detected after stroke (AFDAS) vs. Known atrial fibrillation prior to stroke was evaluated on Ischemic stroke recurrence. Adjusting for pre-stroke oral anticoagulation eliminated the higher hazard for ischemic stroke recurrence previously associated with known atrial fibrillation compared to post-stroke detected AF.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: