Key result
Prophylactic radial cerebral protection enables successful LAAO in a patient with a mitral valve mass.
Why the study?
Many patients with AF cannot tolerate long-term oral anticoagulation, making percutaneous left atrial appendage occlusion an alternative for stroke prophylaxis.
Case Report (n=1)
Demonstrates the feasibility of using a prophylactic cerebral protection device via the radial artery during LAAO in a high-risk patient with a mitral valve mass.
Answers are grounded in this paper and cite their sources.
Feasibility of radial cerebral protection shown in one high-risk LAAO case; hypothesis-generating and should not yet change practice.
Stroke remains a debilitating complication from atrial fibrillation (AF), and AF-related strokes are responsible for over 15% of all stroke cases in the United States.1,2 While systemic oral anticoagulation can mitigate the risk of stroke, many patients cannot tolerate these medications. Percutaneous left atrial appendage occlusion (LAAO) is an alternative to oral anticoagulation for stroke prophylaxis in AF patients who cannot tolerate these medications long-term. In the United States, the WATCHMANTM (Boston Scientific, Marlborough, MA) for LAAO is the only device currently approved by the United States Food and Drug Administration for this indication.
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Shah et al. (2021) conducted a case report in Atrial fibrillation with a mitral valve mass (n=1). Prophylactic cerebral protection device via the radial artery during LAAO was evaluated. A prophylactic cerebral protection device was successfully used via the radial artery during left atrial appendage occlusion in a patient with a mitral valve mass.
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