Key result
Prior MI and diabetes linked to up to ~94% higher breast cancer mortality among survivors.
Why the study?
Does a history of diabetes or myocardial infarction increase mortality in breast cancer survivors?
Cohort (n=8,952)
Yes
Does a history of diabetes or myocardial infarction increase mortality in breast cancer survivors?
Hazard Ratio: 1.48 (95% CI 1.18–1.87)
A history of diabetes or myocardial infarction is associated with significantly increased breast cancer-specific mortality in a multiethnic cohort of breast cancer survivors.
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May warrant closer monitoring of breast cancer survivors with diabetes or prior MI; extends observational data but leaves causal effects and interventions open.
Wu et al. (2014) conducted a cohort in Breast cancer (n=8,952). History of diabetes vs. No history of diabetes was evaluated on Breast cancer-specific mortality (HR 1.48, 95% CI 1.18-1.87). A history of diabetes (HR 1.48; 95% CI 1.18-1.87) or myocardial infarction (HR 1.94; 95% CI 1.27-2.97) increased the risk of breast cancer-specific mortality among breast cancer survivors.
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