Key result
Rare primary left atrial intimal sarcoma presents with recurrent ischemic strokes and fatal pulmonary thromboembolism.
Why the study?
Primary cardiac sarcomas are rare and cerebral infarction complicated with brain metastasis is exceptionally uncommon.
Case Report (n=1)
Highlights a rare case of primary cardiac sarcoma complicated by cerebral infarction and brain metastasis.
Raises suspicion for cardiac sarcoma in recurrent embolic strokes; single case leaves open evidence-based management strategies.
Primary cardiac tumours are rare; 75% of primaries are benign mesenchymal, mostly myxomas. Primary sarcomas are the second most frequent type. Only a few hundred primary cardiac sarcomas have been reported, most diagnosed by autopsy. Sarcomas of the intima are polypoid mesenchymal masses anchored to a vessel or the cardiac wall. To our knowledge, there is a unique report of primary cardiac Sarcoma complicated with cerebral infarction and cerebral metastatic disease. Metastases show a preference for lung, liver, and mediastinum, but the brain is usually a sanctuary. We describe a female in her forty’s with recurrent stroke associated with a cardiac sarcoma, also presenting brain metastases, who died a year after starting the problem by pulmonary thromboembolism.
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Marcela et al. (2022) conducted a case report in Left atrial sarcoma with recurrent stroke and brain metastasis (n=1). Surgical resection and radiotherapy was evaluated on Clinical outcome. A female patient in her 40s with a rare primary left atrial intimal sarcoma presented with recurrent ischemic strokes and brain metastases, ultimately dying from pulmonary thromboembolism one year after symptom onset.
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